This listing is for the 1 oz small bottle. My Pain Relief tinture is a natural potent pain reliever made of 75% Lactuca Virosa wild lettuce from our homestead, along with 25% white willow bark. The bark of white willow contains salicin, which is a chemical similar to aspirin (acetylsalicylic acid) offering powerful pain-relieving & anti-inflammatory plant compounds (flavonoids). The wild lettuce contains lactucin and lactucopicrin which are bitter substances that act on the central nervous system to produce pain-relieving and sedative effects. Can be taken as needed. Made from my genuine wild lettuce. Flavor is bitter so many prefer to take in tea. Shown to aid in pain management and stress relief Beneficial to help ween off prescription pain medications. Do your own research on the ingredients in this product to make the best decision for the pain relief you need.